Diagnostic antibodies and antigens for gastric disease testing: pepsinogen I (PG I), Pepsinogen II (PG II), Gastrin 17 (G17), trefoil factor 1 (TFF1), Gastrin (G100)

Gastric disorders are the most common disease leads to the death. Most death of gastric disease is mostly due the diagnosis at late-stage. The diagnosis of Gastric disease at early-stage is delayed due to the lack symptoms and effective diagnostic technique. The traditional technology, including endoscopic examination and gastroscopic biopsy are invasive to screen large population. Hence, biomarkers such as pepsinogen I, Pepsinogen II, Gastrin 17, trefoil factor 1, Gastrin and so on have been developed to detect the gastric diseases at an early stage for large population to significantly reduce the death caused by gastric cancer. However, the detection of these marker proteins from different samples may benefit from ELISA, Lateral flow immunoassay (LFIA), colloidal gold immunochromatographic assay, Chemiluminescent immunoassay (CLIA), turbidimetric inhibition immuno assay (TINIA), immunonephelometry and POCT.

Classification: PG I PG II G17 TFF1 G100

pepsinogen I (PG I)

Cat No.	Species	Biomarker	Disease	Cat No.of Antigen	Bioactivity validation of Antigen	Cat No.of Antibodies	Bioactivity validation of Antibodies	Order
GMP-h-PG-I	Human	pepsinogen I (PG I)	atrophic gastritis, pernicious anemia, intestinal metaplasia, dysplasia, gastric polyps, and gastric cancer	GMP-h-PG-I-Ag01: Recombinant human PG I Protein	pepsinogen I (PG I) antibodies binding, Immunogen in Sandwich Elisa, lateral-flow tests,and other immunoassays as control material in PG I level test of Gastric disease(atrophic gastritis, pernicious anemia, intestinal metaplasia, dysplasia, gastric polyps, and gastric cancer) and related syndrome evaluation.	GMP-h-PG-I-Ab01; GMP-h-PG-I-Ab02: Anti-human PG I mouse monoclonal antibody(mAb)	Human pepsinogen I (PG I) antigen binding, ELISA validated as capture antibody and detection antibody. Pair recommendation with other pepsinogen I (PG I) antibodies in PG I level test of Gastric disease (atrophic gastritis, pernicious anemia, intestinal metaplasia, dysplasia, gastric polyps, and gastric cancer) and related syndrome evaluation.

Pepsinogen II (PG II)

Cat No.	Species	Biomarker	Disease	Cat No.of Antigen	Bioactivity validation of Antigen	Cat No.of Antibodies	Bioactivity validation of Antibodies	Order
GMP-h-PG-II	Human	Pepsinogen II (PG II)	pernicious anemia	GMP-h-PG-II-Ag01: Recombinant human PG II Protein	Pepsinogen II (PG II) antibodies binding, Immunogen in Sandwich Elisa, lateral-flow tests,and other immunoassays as control material in PG II level test of Gastric disease(pernicious anemia) and related syndrome evaluation.	GMP-h-PG-II-Ab01; GMP-h-PG-II-Ab02: Anti-human PG II mouse monoclonal antibody(mAb)	Human Pepsinogen II (PG II) antigen binding, ELISA validated as capture antibody and detection antibody. Pair recommendation with other Pepsinogen II (PG II) antibodies in PG II level test of Gastric disease (pernicious anemia) and related syndrome evaluation.

Gastrin 17 (G17)

Cat No.	Species	Biomarker	Disease	Cat No.of Antigen	Bioactivity validation of Antigen	Cat No.of Antibodies	Bioactivity validation of Antibodies	Order
GMP-SMT-G17	Human	Gastrin 17 (G17)	Chronic atrophic gastritis (CAG)	GMP-SMT-G17-Ag01: BSA-Gastrin 17 (G17) GMP-SMT-G17-Ag02: OVA-Gastrin 17 (G17)	Competitive immunoassay-validated hapten-carrier conjugates [BSA-&OVA-Gastrin 17 (G17)], Gastrin 17 (G17) antibodies binding, Immunogen in Competitive immunoassay validation, Elisa, lateral-flow tests,and other immunoassays as control material in G17 level test of Gastric disease (Chronic atrophic gastritis (CAG)) and related syndrome evaluation.	GMP-SMT-G17-Ab01: Anti-Gastrin 17 (G17) mouse monoclonal antibody(mAb)	Human Gastrin 17 (G17) binding, in Competitive immunoassay validation, Elisa, lateral-flow tests, and other immunoassays in G17 level test of Gastric disease (Chronic atrophic gastritis (CAG)) and related syndrome evaluation.

trefoil factor 1 (TFF1)

Cat No.	Species	Biomarker	Disease	Cat No.of Antigen	Bioactivity validation of Antigen	Cat No.of Antibodies	Bioactivity validation of Antibodies	Order
GMP-SMT-TFF1	Human	trefoil factor 1 (TFF1)	Bile Reflux and Gastric Ulcer	GMP-SMT-TFF1-Ag01: BSA-trefoil factor 1 (TFF1) GMP-SMT-TFF1-Ag02: OVA-trefoil factor 1 (TFF1)	Competitive immunoassay-validated hapten-carrier conjugates [BSA-&OVA-trefoil factor 1 (TFF1)], trefoil factor 1 (TFF1) antibodies binding, Immunogen in Competitive immunoassay validation, Elisa, lateral-flow tests,and other immunoassays as control material in TFF1 level test of Gastric disease (Bile Reflux and Gastric Ulcer) and related syndrome evaluation.	GMP-SMT-TFF1-Ab01: Anti-trefoil factor 1 (TFF1) mouse monoclonal antibody(mAb)	Human trefoil factor 1 (TFF1) binding, in Competitive immunoassay validation, Elisa, lateral-flow tests, and other immunoassays in TFF1 level test of Gastric disease (Bile Reflux and Gastric Ulcer) and related syndrome evaluation.

Gastrin (G100)

Cat No.	Species	Biomarker	Disease	Cat No.of Antigen	Bioactivity validation of Antigen	Cat No.of Antibodies	Bioactivity validation of Antibodies	Order
GMP-h-G100	Human	Gastrin (G100)	gastrinoma	GMP-h-G100-Ag01: Recombinant human G100 Protein	Gastrin (G100) antibodies binding, Immunogen in Sandwich Elisa, lateral-flow tests,and other immunoassays as control material in G100 level test of Gastric disease(gastrinoma) and related syndrome evaluation.	GMP-h-G100-Ab01; GMP-h-G100-Ab02: Anti-human G100 mouse monoclonal antibody(mAb)	Human Gastrin (G100) antigen binding, ELISA validated as capture antibody and detection antibody. Pair recommendation with other Gastrin (G100) antibodies in G100 level test of Gastric disease (gastrinoma) and related syndrome evaluation.